Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis.
نویسندگان
چکیده
We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.
منابع مشابه
Congenital toxoplasmosis.
Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...
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Background: To evaluate whether the treatment of the pregnant women associated with a lack of monitoring for toxoplasmosis seroconversion affected the prognosis of the patients Methods: Cohort study with 292 newborns at risk for congenital toxoplasmosis, in Goiânia-GO (Brazil), between October 2003 until October 2011. We carried out statistical analysis in order to test the efficacy of maternal...
متن کاملAssociation between prenatal treatment and clinical manifestations of congenital toxoplasmosis in infancy: a cohort study in 13 European centres.
AIM To determine the effectiveness of prenatal treatment for clinical manifestations of congenital toxoplasmosis. METHODS We prospectively identified 255 live-born infants with congenital toxoplasmosis using prenatal or neonatal screening. We determined the effect of prenatal treatment on the risks of intracranial or ocular lesions in infancy, accounting for gestational age at maternal seroco...
متن کاملEffectiveness of prenatal treatment for congenital toxoplasmosis: a meta-analysis of individual patients' data.
BACKGROUND Despite three decades of prenatal screening for congenital toxoplasmosis in some European countries, uncertainty remains about the effectiveness of prenatal treatment. METHODS We did a systematic review of cohort studies based on universal screening for congenital toxoplasmosis. We did a meta-analysis using individual patients' data to assess the effect of timing and type of prenat...
متن کاملPrenatal Treatment for Serious Neurological Sequelae of Congenital Toxoplasmosis: An Observational Prospective Cohort Study
BACKGROUND The effectiveness of prenatal treatment to prevent serious neurological sequelae (SNSD) of congenital toxoplasmosis is not known. METHODS AND FINDINGS Congenital toxoplasmosis was prospectively identified by universal prenatal or neonatal screening in 14 European centres and children were followed for a median of 4 years. We evaluated determinants of postnatal death or SNSD defined...
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ورودعنوان ژورنال:
- Clinical and diagnostic laboratory immunology
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2002